Master Project

place holder

Quality Control Internship at F. Hoffmann-La Roche

Bonds between passionate people transform ambition into progress.

• Growth Direct II System Optimization

• Managing international stakeholder engagement and representation of local interests

• Internal Time-to-Result Study Design which aims to increase environmental monitoring throughput by 2 x

• Driving Projects and SOP-Changes

• Implementing the Kanban logistical system to improve workflow routines

• Building a company internal network to ensure that knowledge is attained fast and reliable

• Website creation to facilitate efficient knowledge transfer

• Organisation of meetings, events and presentations

Visiting Researcher at the University of Toronto

Structurally characterizing the ectodomain of Guanylil Cyclase-C membrane protein, in complex with clinically approved cystine knot ligands Linaclotide and Plecanatide.

• Plasmid design, DNA preparation, and transfection of mammalian cell cultures

• Protein purification, via Ni-NTA and SEC

• Protein vitrification for cryoEM using a Vitrobot MKIV

• Assisting in cryoEM screening and data collection using both
  Glacios and Krios microscopes

• Hands on data processing of cryoEM data in CryoSPARC

• Computational analysis of AlphaFold models

• Computational engineering of rigid BRIL fusions for fiducialisation of ECD

Master's Degree in Life Sciences

Where my interest in protein structures became a scientific direction.

• Molecular Dynamics: Analyzing the highly flexible Twitching Kinase

• X-Ray Structural elucidation of Tet-R Transcription factor

• Excursion to Paul Scherrer Institute in Villigen (CH)

• High-resolution Diffusion NMR spectroscopy of PFAS molecules

• Scientific Computing with Python Project: DOSY NMR - Analysis UI

• Bioinformatics: RNASeq analysis of CDK-12 mutations in prostate cancer

• Lectures: Disease Bio, Biochemistry III, Biopolymer Chemistry

Student & Research Assistant in Sydney

From Western Blots and whale watching to validating LC-MS retention times predictions.

• Lectures: Drug Desing & Devlopment, Microbes in Health and Disease & Australian Sports and Culture

• Western blotting and Immunohistochemistry (IHC) and image analysis

• Assisting with mice handling for Inflammatory Bowel Disease Studies

• Validation of AI-predicted LC-MS retention times

• Biomarker evaluation in inflammatory bowel disease research

• Neutrophil Extracellular Traps & Protein-arginine Deiminase Type-4 inhibition

• Handling and interpretation of patient-derived blood sample data

• Literature research, data analysis and presentation

Bachelor's Degree in Life Sciences

Where science started to shape my world.

• Undergrad Student

• International Office Committee Member

• Research Assistant in Psychoneuroimmunology

• Tutor in inorganic Chemistry

Bachelor Thesis

Analysis of PBMC Composition in Post-COVID Patients

Health Psychology AG Wirtz and Molecular Toxicology AG Bürkle

Social work and Coaching

Voluntary Year in Elementary School

• Gymnastics Coach

• Football Coach

• Social and Educational Support
  for 1st - 4th graders
  

Refugee Supervisor

Teaching German values and providing emotional support to unaccompanied refugees from the Middle East, Ukraine and Africa

• Communication

• Project Management

• Organizing and travelling on multiday city excursions

• Mental support

• Dealing with government agencies
  

Let's connect

Contact me for questions, networking or in case you need a gymbuddy